Description : The Connectivity Map, or CMap, is a resource that uses transcriptional expression data to probe relationships between diseases, cell physiology, and therapeutics. The changes in gene expression, or “signatures,” that arise from a disease, genetic perturbation (knockdown or overexpression of a gene) or treatment with a small molecule are compared for similarity to all perturbational signatures in the database. Perturbations that elicit highly similar, or highly dissimilar, expression signatures are termed “connected”; their related transcriptional effects suggest they confer related physiological effects on the cell. Our goal is to use these connections to uncover novel treatments for a variety of diseases, including cancers, neurological diseases, and infectious diseases. (https://clue.io/cmap)
Created : Dec. 16, 2022, 1:50 p.m.
Owner : tdarde
| Public |
https://clue.io/data/NLT#NLT_B [more] |
tdarde | Dec. 16, 2022, 1:54 p.m. |
| Public |
https://clue.io/data/NLT#NLT_B [more] |
tdarde | Dec. 16, 2022, 1:54 p.m. |
| Public |
https://clue.io/data/NLT#NLT_B [more] |
tdarde | Dec. 16, 2022, 1:55 p.m. |
| Public |
https://clue.io/data/NLT#NLT_B [more] |
tdarde | Dec. 16, 2022, 1:55 p.m. |
| Public |
https://clue.io/data/NLT#NLT_B [more] |
tdarde | Dec. 16, 2022, 1:55 p.m. |